GO:0030433 biological_process ubiquitin-dependent ERAD pathway
| PAG Title | GO:0030433 biological_process ubiquitin-dependent ERAD pathway |
| PAG ID | TAX020516 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome. |
| Species | Homo sapiens |
| nCoCo Score | 700 |
| Base PAG ID | TAX020516 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
">
Something else? Please send us an email!